SLNB is a minimally invasive and accurate alternative to axillary lymph node dissection (ALND) and is associated with reduced morbidity compared with axillary dissection. It is thought that if breast cancer cells were to escape into the lymphatic system, they would travel to the sentinel nodes before moving on to other nodes and the sentinel lymph node (SLN) technique is based upon the observation that tumour cells migrating from a primary tumour metastasise to one or a few lymph nodes before involving other lymph nodes. What is Sentinel Lymph Node Biopsy (SLNB)?Ī sentinel lymph node biopsy (SLNB) is a procedure in which the sentinel or ‘guardian’ lymph nodes are identified, removed, and pathologically examined to determine whether cancer cells are present. Usually, there is more than one sentinel lymph node. The sentinel node/s are the lymph nodes that the breast drains to first, and are the first lymph nodes to which cancer cells are most likely to spread from a primary breast tumour. Sentinel Lymph Node Biopsy for Patients With Early-Stage Breast Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update (2017) What is a sentinel lymph node? Management of the Malignant Axilla in Early Breast Cancer-ABS Consensus Statement (2015) ![]() Axillary Surgery including Sentinel Node BiopsyĪxillary Surgery Following Neoadjuvant Chemotherapy- Multidisciplinary Guidance (2019)ĪSBrS Consensus Guideline on Axillary Management for Patients With In-Situ and Invasive Breast Cancer: A Concise Overview (2022)
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